Helicobacter Forums

You often hear about antibiotic resistant bacteria emerging because we overuse said antibiotics and the bacteria adapted to it.
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However since evolution isnt proactive that shouldnt be true, antibiotic resistant bacteria must have existed before the widespread use of antibiotics or am i mistaken?

it's the environment given that created the features required to survive.
H. pylori evolved to survive in acids in the stomach where it's acidic.

when antibiotics are abundant, the bacteria must learn to live with it or perish.

some antibiotic resistance can be transferred. If the bacteria carrying the antibiotic-resistant genes start spreading the "survival" skill set. Then soon all those who accept the new skill will learn how to survive when exposed to antibiotics.

Then again, in the world of biology, it's either use it or lose it. If you do not provide the environment to maintain the resistance, they will eventually loss the ability. it's a waste of energy to produce anti-antibiotics if they are not used.

You’re partly right: antibiotic-resistant bacteria already existed before widespread antibiotic use due to random mutations. However, when antibiotics are used extensively, they create pressure through natural selection—susceptible bacteria are killed, while resistant ones survive and multiply. So antibiotics don’t directly create resistance, but they make existing resistant strains much more common.