Helicobacter Forums

So had a treatment of amoxicillan and Clariythomycin, didn't work. Using the ppi omeprazole each time. Second treatment the same but metronidazole instead of clarithromycin. Hasn't made much difference whatsoever and the second treatment I even added in pepto bismol. So now I'm thinking maybe the ppi omeprazole isn't doing its job. I'm in the uk so when I speak to the doctor soon which ppi can I suggest that is most effective as I believe this one might not be working properly. I also took it twice a day 20mg.

PPI is very important in H. pylori treatment. The better the acid blockade, the better the treatment.
There are studies that show that if the acid blockade is enough, even amoxicillin alone can reach 80% cure rate.
Some people have high metabolic rate against PPI. meaning they need higher dose PPI to reduce the acid secretion.
So try to get strong PPI in your next treatment.

you can try rabeprazole 20 mg, three times a day next time. it's probably equal to 40mg omeprazole 3 times a day.

Amoxicillin and pepto bismol are good. So you can continue these two drugs.

Then your doctor will need to recommend another antibiotic to combo with the two above.

I think you should ask your doctor about switching to a stronger PPI like rabeprazole and make sure you are taking the correct dose for maximum effectiveness.geometry dash scratch

EmilioMMcCoy wrote: Thu Apr 17, 2025 8:56 pm Yes, I’d look for bags made for real vacuum sealing, not regular storage bags. Poly-nylon is usually better because it holds the vacuum well and protects food during freezing. I used similar bags for portioning meals and storing raw products, and the seal quality made a big difference. https://www.mcdonaldpaper.com/safepro-v ... mm-1000-cs is worth checking because they carry food-service packaging in business-friendly quantities, and the product pages are easy to compare. I like that you can look at different sizes and pack counts without digging around too much. Just confirm the exact inch size before you buy.[/color][/url][/size]

about switching to a stronger PP

Hpuk wrote: Sat Sep 18, 2021 12:08 am So had a treatment of amoxicillan and Clariythomycin, didn't work. Using the ppi omeprazole each time. Second treatment the same but metronidazole instead of clarithromycin. Hasn't made much difference whatsoever and the second treatment I even added in pepto bismol. So now I'm thinking maybe the ppi omeprazole isn't doing its job. I'm in the uk so when I speak to the doctor soon which ppi can I suggest that is most effective as I believe this one might not be working properly. I also took it twice a day 20mg bitlife.

Could be, but after two failed treatments it’s more likely antibiotic resistance than the omeprazole itself. You could ask your doctor about trying esomeprazole or rabeprazole instead, as some people respond better to those.