Helicobacter Forums

What treatment can I have without amoxicillin?

There are several wasy to treat H.pylori without using penicillin. Firstly, you still need to block acid so that part of the treatment remains. Clarithromycin with metronidazole for 10 days is an alternative choice. After that combinations of PPI, quinolone and rafabutin have been successful. Bismuth, tetracycline and metronidazole with a PPI is a tried and tru combination. Furazolidone is useful. It becomes rather specialised as we go down the list. An article about treatment can be found on-line here: http://www.kibion.com/Download.aspx?id=8985 (Stenstrom, Mendis, Marshall, Australian Family Physician 2008).

What about Amoxicillin and penicillin allergy and acute intermittent porphyria.
Due to porphyria I can not use metronidazole,tetracycline... (check http://www.drugs-porphyria.org/index.php)
What are your suggestion for treament of Helicobacter infection?

The web site you listed should be checked for each antibiotic you want to use. Also, if there is any doubt that you are really allergic to amoxicillin you should see an allergist to absolutely confirm you are allergic because amoxicillin is the best baseline treatment. Rabeprazole is the least cytochrome-active proton pump inhibitor (PPI) as far as I know. Bismuth (De-Nol or Pepti-Bismol) should be OK. The other antibiotics are green-yellow mostly but a few reach the orange (be careful!) zone as far as risk is concerned. I recommend PPI-clarithromycin-metronidazole/tinidazole as the next treatment but see what your doctor says. Print out the info pages in color for each drug as they are listed on the porphyria information site site and take them to your doctor. Here is that link again: http://www.drugs-porphyria.org/language ... .php?l=gbr