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Why two or three antibiotics instead of one ?

Posted: Sun Aug 19, 2018 8:38 pm
by museaddict
I don't understand why we have to take 2 or 3 antbiotics to kill the bacteria instead of one ??
I think the H.pylori can't resist to Amoxicillin so why we take the other antibiotics ??

Re: Why two or three antibiotics instead of one ?

Posted: Sun Aug 19, 2018 11:11 pm
by Helico_expert
good question and it's still being asked many times in almost every meeting.

when amoxicillin is used with PPI, as a duo therapy, the cure rate is about 50%. Then someone figured out that with 2 antibiotics and a PPI, a triple therapy, can boost the cure rate to 80%. and since then, treatment of H. pylori is always with at least 2 antibiotics and a PPI.