False Negative on a biopsy? Really need some help...
Posted: Tue Jul 17, 2018 2:28 am
Like many of you, I have been dealing with hell for a while now - I'm female, and in my early 40s. This all started for me a little over two years ago, and my symptoms have gotten increasingly worse:
* constant nausea
* ridiculously bloated
* acid reflux that has zero help from PPIs, Tums, etc.
* constant belching
* weird bowel movements - I haven't had a solid BM in months. Usually it comes out pencil thin, flaky, or just disintegrates in the bowl.
* occasional vomiting
* constant burning pain in abdomen. It hurts if I don't eat. It hurts if I eat.
* really bad burning pain under right rib (much better after gallbladder removed, but not wholly gone)
* "scraped" feeling inside my intestines. I tell my husband it feels like I swallowed a pine cone that is moving through my insides.
* constant fatigue and tired feeling (may be due to me not eating much)
* weight loss; have lost 30 pounds and am now reaching the point where I can't afford to lose much more
My doctors have done all kinds of colonoscopies, endoscopies, and other fun stuff. I've been given PPIs, which did nothing. Finally, as a "Well, we dont' know what's wrong with you, but your gallbladder seems to be in bad shape" response, I had it removed a couple of months ago. I felt a lot better the first few weeks, and then it all went to hell again (my personal suspicion: the antibiotics they gave me during the surgery knocked whatever the heck I have down a few notches before it started growing again).
During one of the endoscopies about 4 months ago, they finally did a biopsy to check for H. pylori. Note: during that time, I had been on PPIs as well as a minor antiobiotic (Macrodantin) for something else. The test result was negative.
My questions:
1. Does this sound like H. pylori, based on the symptoms above?
2. I did some poking online, and it sounds like if you're on PPIs, it can give you a false negative. True?
Any help is greatly appreciated...
* constant nausea
* ridiculously bloated
* acid reflux that has zero help from PPIs, Tums, etc.
* constant belching
* weird bowel movements - I haven't had a solid BM in months. Usually it comes out pencil thin, flaky, or just disintegrates in the bowl.
* occasional vomiting
* constant burning pain in abdomen. It hurts if I don't eat. It hurts if I eat.
* really bad burning pain under right rib (much better after gallbladder removed, but not wholly gone)
* "scraped" feeling inside my intestines. I tell my husband it feels like I swallowed a pine cone that is moving through my insides.
* constant fatigue and tired feeling (may be due to me not eating much)
* weight loss; have lost 30 pounds and am now reaching the point where I can't afford to lose much more
My doctors have done all kinds of colonoscopies, endoscopies, and other fun stuff. I've been given PPIs, which did nothing. Finally, as a "Well, we dont' know what's wrong with you, but your gallbladder seems to be in bad shape" response, I had it removed a couple of months ago. I felt a lot better the first few weeks, and then it all went to hell again (my personal suspicion: the antibiotics they gave me during the surgery knocked whatever the heck I have down a few notches before it started growing again).
During one of the endoscopies about 4 months ago, they finally did a biopsy to check for H. pylori. Note: during that time, I had been on PPIs as well as a minor antiobiotic (Macrodantin) for something else. The test result was negative.
My questions:
1. Does this sound like H. pylori, based on the symptoms above?
2. I did some poking online, and it sounds like if you're on PPIs, it can give you a false negative. True?
Any help is greatly appreciated...