Helicobacter Forums

Hello.

Apriori sorry for the long text.

Please help.

I want to ask some advice in here, because the standart way of treating disease by going to a doctor seems useless in my case. See, i live in Russia. So getting adequate medical care is a very complicated thing because either of total incompetence of doctors in public clinics or unjustified and inadequately expensive methods of diagnosis and treatment in private clinics, which are aimed exclusively at "sticking" patient to a particular clinic to suck money from him. And i am a phd student thinking about how to pay rent.

I am 24. First was diagnosed with chronic gastritis when i was 12. Twice a year i experienced constant nausea vithout catually vomiting and that was the only problem. I was tested positive for HP. Doctor prescripted some antibiotics and other pills(i think those were de-nol & omeprazole). But i do not remember exactly. So i once a year did endoscopy and 3 or 4 years in a row received antibiotics and other pills. The problem is that i do not remember what antibiotics those were exactly. Then i felt a little better and from 16 to 21 years old i almost forgot about my gastritis.

But when i turned 21 problems with stomach came back. This time it was not nausea, but apart from standard mild symptoms the biggest problem was abdominal distention, extreme swelling in the stomach, constant flatulence and problems with defecation constantly changing from constipation to diarrhea. Usually 3 times a day or even more and in small quantities. Usually starting after noon right after lunch. So it started causing constant discomfort combining this constant the urge to defecate and flatulence. Usually discomfort and gas is felt in the left bottom part of torso. And feces were more sticky and almost all rainbow colors even had shades of green, red, yellow or almost white. Of cource quality of life has declined sharply. First of all i thougth i was infected with worms from a cat i brought home from the street, which i am by the way allergic to. Stool samples didnt show any. Only blood testing showed antigen, so i took anthelmintic pills, but it didn't help.

When i again went to see a doctor he again perfomed endoscopy and he said that i again had erosive gastritis stomach and duodenum. Again prescribed a lot of medications but it did not reduce sympthoms. Only when i was taking DE-NOL i felt better and sympthoms were almost gone. But when i was giving it up each time flatulence and swelling and defecation problems were coming back again. Now it is difficult to say if i have HP or not. In a short period of time i had 4 biopsies while endoscopy and two of them were positive, two negative. And it is taking into account that i didnt take ANY medications at all in 6 weeks.

I would be very grateful if qualified competent person could give me some advice and answer these questions.

- In Russia breath tests are much less common thing then endoscopy. Wich method is better? Because my doctor acted like breath tests are kind of quackery.
- How long can i take DE-NOL to reduce sympthoms. Do a have to make 2 month breaks after each 8 weeks of therapy because of accumulation of bismuth?
- What antibiotics are best for quadriple therapy in my situation? What should i take with omeprazole & de-nol? Taking into account that i may be resistant to a lot of antibiotics, because i do not remember what i was taking when i was 12-16. And i also took some strong antibiotics becaue of other diseases: Lyme borreliosis, furunculosis, urological inflammations. Again i do not remember what antibiotics exactly i took, but among them there were tetracyclin, Trichopolum, amoksiklav, others... so i might be resistant to a lot of those. I think i should take amoxicyclin because HP cant be resistant to it and what else?
- If i took DE-Nol for 2 weeks, can i start quadriple therapy tomorrow? Or should i wait?
- What are ways to reduce flatulence and swelling besides Simethicone?

Thanks A lot!

Extremely grateful for your help.

Eric

Breath test is very safe and accurate. some people are worried about c14 being radioactive and switch to c13. Both carbon isotopes are actually fine.

Denol is a type of metal that has anti bacterial effect. Some people even take it during their travel as a preventive care. It can kill H. pylori in your stomach and H. pylori will never develop resistance to it. So, if you are planning to do a breath test, you will need to stop Denol for at least 2 weeks before breath test.

Denol has a side effect of giving very dark stool. Some doctor are worried because they will think the patient has internal bleeding, which usually gives dark stool too.

for your case, it is best you perform another endoscopy and request for antibiotic sensitivity test. That will accurately tell you what antibiotics you should take for H. pylori eradication. Since H. pylori will not gain resistance to Denol and Amoxicillin, you can always have Denol, Amoxicillin and one other antibiotic (Tetracycline, furazolidone, rifabutin or ciprofloxacin) in your next quadruple therapy. Discuss with your Specialist for the availability.

T. Hanks a lot for your help!

Hello again. I just have couple more questions.

For my treatment i chose 14-days quadriple therapy of amoxicillin 1000x2, claritromicin 500x2, bismuth(de-nol) 240x2 & omeprazole 20x2. Started it yesterday.

Can i take bismuth the same time with antibiotics, does it or does it not affect the absorbtion is antibiotics?
Which way to take antibiotics is better before, after or during meal?
How can i reduce or stop antibiotic-related diarrhea? It started already.

Thanks a lot.

you may start bismuth together with other antibiotics.
We advise our patients to take it with or after meal.
There is no quick way to stop antibiotic-related diarrhea. But once you stop the antibiotics, the diarrhea will go away.

Thanks again for your advice. Today is the last day of my therapy. I hope i killed that bacteria good)

I read in some articles that specialists advise after the antibacterial treatment for two more weeks continue to take only PPI like omeprazole. Do you think i shall do the same? What good is it?

patients who are suspected with ulcers should continue to take PPI for a month until ulcer heals. If you have ulcer, the PPI will stop the acid from further damaging your ulcer and give your ulcer a chance to heal.

If your doctor did not prescribe more PPI for you, you are probably not suspected for ulcer. Remember to do a urea breath test one month later to confirm the eradication.