allicin vs Helicobacter
Posted: Wed Mar 21, 2012 9:11 pm
To be clear... I'm not fan of Garlic... But I have found a few works which show that allicin is able to kill HP in concentartion about 5mg/L (in vitro study)... and later I was looking how it looks in praticse and in one study they use
- garlic oil with content of Allicin 0,8 mg/L.... three times in day ... Conclusion it dosent work at all...
in second one :
Capsules with garlic powder (something about 500mg three times day or something like that) Conclusion: It dosent work at all
Another study use 10 sliced Cloves of Garlic... UBT test show there is no improvment...
Another study show eradication rate of 23% with dose of 4,2mg Allicin... I read it but I found it is poor Quality... most data in tabels do not suit...
My conclusion:
First study that dose is definitevly to low... If you want show that something dosent work you have to use in amount that will not working...
Second study: Enzyme allinase dont work properly at low pH and it is possible that capsules are realsed first in small intestine... they should mix capsule content with water...
Third study: That cloves were sliced not crushed... it makes huge differnces
Last study apart from many mistakes shows that even 4.2 mg allicin can be quite promissing
And now some core
https://docs.google.com/viewer?url=http ... 0-0113.pdf
Bactericidal effect of amoxicilin is very few mg/L
Why we dosent use few mg amoxicilin tabs, but whole 1 g of amoxicilin...?
What happen when instead of using in clinical study dose of allicin which roughly corespond to concentration which show effect in tube...?
When we assume that loss of ,,killing effect,, of allicin in vivo is the same like of amoxiclin. We should use as well some 1g of allicin... 1 g is probably much to much but when some dose of 100mg allicin show no effect it will be convincing (I mean real allicin not powder not sliced garlic cloves of unknown origin, no garlic oil with low allicin content)
In my opinion all that studies want to show one: Allicin dosent work properly in vivo... and they were design to proof it.
- garlic oil with content of Allicin 0,8 mg/L.... three times in day ... Conclusion it dosent work at all...
in second one :
Capsules with garlic powder (something about 500mg three times day or something like that) Conclusion: It dosent work at all
Another study use 10 sliced Cloves of Garlic... UBT test show there is no improvment...
Another study show eradication rate of 23% with dose of 4,2mg Allicin... I read it but I found it is poor Quality... most data in tabels do not suit...
My conclusion:
First study that dose is definitevly to low... If you want show that something dosent work you have to use in amount that will not working...
Second study: Enzyme allinase dont work properly at low pH and it is possible that capsules are realsed first in small intestine... they should mix capsule content with water...
Third study: That cloves were sliced not crushed... it makes huge differnces
Last study apart from many mistakes shows that even 4.2 mg allicin can be quite promissing
And now some core
https://docs.google.com/viewer?url=http ... 0-0113.pdf
Bactericidal effect of amoxicilin is very few mg/L
Why we dosent use few mg amoxicilin tabs, but whole 1 g of amoxicilin...?
What happen when instead of using in clinical study dose of allicin which roughly corespond to concentration which show effect in tube...?
When we assume that loss of ,,killing effect,, of allicin in vivo is the same like of amoxiclin. We should use as well some 1g of allicin... 1 g is probably much to much but when some dose of 100mg allicin show no effect it will be convincing (I mean real allicin not powder not sliced garlic cloves of unknown origin, no garlic oil with low allicin content)
In my opinion all that studies want to show one: Allicin dosent work properly in vivo... and they were design to proof it.