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Re: C14 UBT and opinions needed

Posted: Fri Apr 22, 2022 6:32 pm
by Ice006
Helico_expert wrote: Tue Apr 19, 2022 2:26 pm
If you are over 50 year old, then you should get an endoscopy done, as a baseline reference. In case you need another endoscopy done when you are 60 or 70, then you have something to compare to and see how much worse it have become.
if you are young, around 30-50, mild symptom, then endoscopy is optional. However, if the doctor suspect that you have an ulcer, or have family history of gastric cancer, then endoscopy is still recommended.
I'm in this age range.
if you decided to take antibiotics and PPI, then you'll need to wait for at least 4 weeks before you go ahead for endoscopy.

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these are the scenarios

Scenario 1.
you have HP and the treatment works.
your endoscopy would see some gastritis. histology will show inflammation retreating. no HP will be since when special stain is used.

Scenario 2.
you have HP and the treatment failed.
your endoscopy would see some gastritis. histology will show active inflammation. HP can be since when special stain is used.

Scenario 3.
You dont have HP. with or without treatment is the same.
your endoscopy may see gastritis. histology may see a bit of inflammation. no HP will be since when special stain is used.
"HP can be since when special stain is used" What does this mean? I don't understand the wording.

So basically, looking at what you're saying, if I'm understand correctly, it's going to change the histology if I take the antibiotics even if I get an endoscopy done 4-8 weeks after taking them?

Also, for scenario 3, is that if I don't take the antibiotics and don't have HP, or is that scenario if I take the antibiotics, but don't have HP?
Thanks a lot for replying. Really appreciate all the awesome help you've given me so far.

Re: C14 UBT and opinions needed

Posted: Tue Apr 26, 2022 11:01 am
by Helico_expert
sorry for the typo... i meant to say even with special HP specific stains, the pathologist will not see HP.

if you have taken antibiotics 4-8 weeks ago, then if the treatment works, your gastritis will gradually recover, which can be revealed by histology.

if the treatment failed, then the gastritis will continue, which can also be revealed by the histology.

Scenario three is without HP. the antibiotics will not change the outcome of histology.