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Quadruple therapy after 2 failed ones

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eps123
Posts: 3
Joined: Sat Jan 06, 2024 6:06 am

Quadruple therapy after 2 failed ones

Post by eps123 »

Hi, I'm from the UK. I started having issues last year, usually with occasional nausea after eating fatty or spicy food.
A few months after it got very bad when I was sick with all kinds of symptoms every day.

H pylori was detected in my stool test and the doctor prescribed 7 days of therapy:
amoxicillin 1000 mg, metronidazole 400 mg, omeprazole 20 mg (all twice a day)

After failing this I went on another one for 10 days:
amoxicillin 1000 mg, clarithromycin 500 mg, omeprazole 20 mg (all twice a day)

After failing the second one (came positive in the stool test) I'm planning to go for a 14 days quadruple therapy.
I have a few questions for Helico_expert regarding the therapy as I want to make sure I have done everything for it to be successful.

1. I want to go with Bismuth this time however here in the UK we only have access to Pepto Bismol.
How should I dose it? One 30 ml cup provided twice a day with antibiotics or should I take more?

2. A higher dose of PPI always gives better results so omeprazole 20 mg twice a day that I used in 2 previous therapies is high enough or should I take something else?

3. Which 2 antibiotics should I use in this therapy, shall I use amoxicillin 1000 mg again or 2 completely different antibiotics and if so which ones?

4. Is there anything else I can use to support the therapy to increase the chances of its success like some biofilm disruptor, probiotics, mastic gum or any dietary tip?

I would be very grateful for any help.

saltysnack
Posts: 3
Joined: Mon Jan 08, 2024 5:12 am

Re: Quadruple therapy after 2 failed ones

Post by saltysnack »

A biofilm buster like NAC can help.

eps123
Posts: 3
Joined: Sat Jan 06, 2024 6:06 am

Re: Quadruple therapy after 2 failed ones

Post by eps123 »

Is NAC to be taken with the therapy or a week before?

eps123
Posts: 3
Joined: Sat Jan 06, 2024 6:06 am

Re: Quadruple therapy after 2 failed ones

Post by eps123 »

Anyone? Helico_expert?

Filiz-isabela-ziya
Posts: 3
Joined: Sat Feb 10, 2024 7:07 am

Re: Quadruple therapy after 2 failed ones

Post by Filiz-isabela-ziya »

Please check out my very detailed quad therapy that worked for me and my son. It’s Under Filiz quad treatment.

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