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Levofloxacin Triple Therapy Side Effects

Posted: Sun Feb 07, 2021 9:05 am
by Tweenie
Hello, Experts:

I’m on day four of triple therapy. I’ve been asked to take these meds for 14 days:

Levofloxacin 500 mg once per day
Amoxicillin 1000 mg twice per day
Pantoprazole 40 mg twice per day

I had an endoscopy done where they performed a culture and sensitivity test and this was the treatment chosen. This will be my second attempt to eradicate. I don’t remember what I took the first time.

My questions are:

1. I have been experiencing quite a bit of nausea with these meds. Will this resolve or stay with me for the fourteen days?
2. How well does this triple therapy work?

Thank you in advance.

Re: Levofloxacin Triple Therapy Side Effects

Posted: Sun Feb 07, 2021 10:26 am
by Helico_expert
you may be experiencing some side effect from the treatment. Continue the treatment if you think the side effect is tolerable. Talk to your doctor if you think you need to. He is responsible for your overall well being.

The treatment is very effective if it's according to the sensitivity testing. In addition, you have a good dose of PPI. However, if you can add bismuth to your treatment, that will boost the cure rate further.

Re: Levofloxacin Triple Therapy Side Effects

Posted: Sun Feb 07, 2021 12:13 pm
by Tweenie
Thank you for answering so quickly. What does bismuth do to boost? I’m assuming you mean Pepto Bismal?

Re: Levofloxacin Triple Therapy Side Effects

Posted: Sun Feb 07, 2021 6:57 pm
by Helico_expert
There are many bismuth compound. Pepto bismol is one of them.

bismuth is a type of heavy metal and doesnt absorb well by our body. So it coats your digestive system and kill off microbes. Not only that H. pylori cannot become resistant to bismuth, bismuth can prevent C. diff, which is a common digestive disease after strong antibiotic treatment.

Re: Levofloxacin Triple Therapy Side Effects

Posted: Sun Feb 07, 2021 10:11 pm
by Tweenie
Thank you, Expert. I’ll check with my doctor. Much appreciate your help.

Re: Levofloxacin Triple Therapy Side Effects

Posted: Mon Feb 08, 2021 12:24 am
by Tweenie
Just one more question. Given that I’m on day five of treatment, is it too late to start the bismuth? If I’m Contact my doctor tomorrow and she agrees, will it be too late to start?

Re: Levofloxacin Triple Therapy Side Effects

Posted: Mon Feb 08, 2021 9:21 am
by Helico_expert
not too late to start. if there are some survival that is becoming resistant to your antibiotics, they will be killed off by the additional bismuth, before they grow up in numbers.

Re: Levofloxacin Triple Therapy Side Effects

Posted: Mon Feb 08, 2021 12:40 pm
by Tweenie
Thanks, expert!

Re: Levofloxacin Triple Therapy Side Effects

Posted: Wed Jun 02, 2021 5:32 am
by Tweenie
Just an update. I finally did a urea breath test after my treatment a few months ago and today, I found out that I’m negative for HP! I’m so glad!

Re: Levofloxacin Triple Therapy Side Effects

Posted: Wed Jun 02, 2021 9:46 am
by Helico_expert
That's fantastic news!
congratulation. How are you feeling now?
you may still have a bit of symptoms.. but that's common. It'll be helpful for the members to share your experience about the H. pylori aftermath.