Toxicosis in H.pylori infection
Posted: Tue Apr 16, 2019 3:55 am
I am looking to get your opinion on a research article by a researcher or H.Pylori. I will link it below to the article. I will be forever greatful if you could spare a couple of minutes to give me your opinion. I don't know who else to ask!
I have been suffering from a mixture of seemingly unrelated symptoms for more than two years.
I had low energy all day, I slept for 16-18 hours every day and still didn't feel refreshed after I woke up. I had headaches and couldn't concentrate or carry out day to day tasks that required mental focus. My stools are all messed up and alternated between constipation and loose stools. Lack of appetite. Lack of interest in creative activities
I visited lot of specialists who ordered a wide array of tests looking to find what's wrong.
All the tests came back negative and the doctors concluded it is one of two things: 1) A psychosomatic illness triggered by a traumatic event or 2) I'm hypochondriac and anorexic and in denial of my symptoms.
I had almost given up on finding a diagnosis and was at the end of my rope as they say. Then one day I found a research article by Mihai Belascu titled -"Toxicosis in H.Pylori infection" and immediately identified with the symptoms mentioned in the patients referred to in the article. I was elated to have finally found some answers.
I visited a gastroenterologist and asked for an H.Pylori investigation. He ordered an endoscopy and the RUT test came back positive. He put me on
the following medication for 14 days.
Amoxicillin, Clarithromycin and Pantoprazole. I immediately saw a major improvement with all my symptoms. My appetite returned and my sleep was a lot more refreshing and my energy levels were better.
But as soon as I stopped the antibiotic course after 14 days all my symptoms gradually returned. I went back to the doctor and he suggested we do a second endoscopy after one month. The second endoscopy came back positive and so he put me on a second round of H.pylori regimen which was Amoxicillin, Levofloxacin and esomeprazole. I saw a slight improvement in the first 3 to 4 days around 20 to 30 percent but then the improvement stopped and all symptoms went back to their original level of severity.
When I went back to the doctor, he said none of my symptoms are typical to an H.Pylori infection. Also, H.Pylori infection rate is around 50 percent in my country and so there is a 50 percent chance that he himself is positive with h.pylori. So my symptoms could not be a result of H.Pylori infection and my lack of appetite is probably psychiatric in origin, likely anorexic. When I mentioned that I do not think I am fat and in fact I think I am thinner than I what I like to be he just brushed aside my protest, which I admit made me feel a bit like punching him.
After two rounds of treatment failure, I am stuck on what to do next. I want to add Bismuth to my treatment regimen but it looks like it is not staple component in H.Pylori eradication treatment in my country, so I couldn't find it anywhere.
I am hoping to find someone on this forum who had more extensive experience in diagnosing and treating H.Pylori. I am attaching the article I cited above to this post and I hope the doctors, researchers or any other experts on H.Pylori can take a look and give me your opinion.
I have been suffering from a mixture of seemingly unrelated symptoms for more than two years.
I had low energy all day, I slept for 16-18 hours every day and still didn't feel refreshed after I woke up. I had headaches and couldn't concentrate or carry out day to day tasks that required mental focus. My stools are all messed up and alternated between constipation and loose stools. Lack of appetite. Lack of interest in creative activities
I visited lot of specialists who ordered a wide array of tests looking to find what's wrong.
All the tests came back negative and the doctors concluded it is one of two things: 1) A psychosomatic illness triggered by a traumatic event or 2) I'm hypochondriac and anorexic and in denial of my symptoms.
I had almost given up on finding a diagnosis and was at the end of my rope as they say. Then one day I found a research article by Mihai Belascu titled -"Toxicosis in H.Pylori infection" and immediately identified with the symptoms mentioned in the patients referred to in the article. I was elated to have finally found some answers.
I visited a gastroenterologist and asked for an H.Pylori investigation. He ordered an endoscopy and the RUT test came back positive. He put me on
the following medication for 14 days.
Amoxicillin, Clarithromycin and Pantoprazole. I immediately saw a major improvement with all my symptoms. My appetite returned and my sleep was a lot more refreshing and my energy levels were better.
But as soon as I stopped the antibiotic course after 14 days all my symptoms gradually returned. I went back to the doctor and he suggested we do a second endoscopy after one month. The second endoscopy came back positive and so he put me on a second round of H.pylori regimen which was Amoxicillin, Levofloxacin and esomeprazole. I saw a slight improvement in the first 3 to 4 days around 20 to 30 percent but then the improvement stopped and all symptoms went back to their original level of severity.
When I went back to the doctor, he said none of my symptoms are typical to an H.Pylori infection. Also, H.Pylori infection rate is around 50 percent in my country and so there is a 50 percent chance that he himself is positive with h.pylori. So my symptoms could not be a result of H.Pylori infection and my lack of appetite is probably psychiatric in origin, likely anorexic. When I mentioned that I do not think I am fat and in fact I think I am thinner than I what I like to be he just brushed aside my protest, which I admit made me feel a bit like punching him.
After two rounds of treatment failure, I am stuck on what to do next. I want to add Bismuth to my treatment regimen but it looks like it is not staple component in H.Pylori eradication treatment in my country, so I couldn't find it anywhere.
I am hoping to find someone on this forum who had more extensive experience in diagnosing and treating H.Pylori. I am attaching the article I cited above to this post and I hope the doctors, researchers or any other experts on H.Pylori can take a look and give me your opinion.