Bromelain: Effect on amoxicillin?
Posted: Thu Feb 28, 2019 2:20 am
Hello:
I usually take the supplement Bromelain to help with inflammation.
I've just read several medical articles which assert that Bromelain can potentiate Amoxicillin (and Tetracycline) and increase its levels in blood. In fact, it is often used to do just that.
My concern is that it might also increase its side-effects. Especially since I'm now taking 2 grams of it daily.
However , I also read-in journal article- that it can decrease side-effects of these antibiotics, as well as potentiating them:
===================
"Bromelain increases bioavailability and reduces the side effects that are associated with various antibiotics (12,13)"[
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4998156/
[cut and paste above link into browser for it to work]
==================
So far , this is only source I have found for reducing side effects. Much of the literature only references increasing blood levels of Amoxicillin.
An article surveying the medical literature on Bromelain does discuss its potentiating effects on some antibiotics and does discuss a study where some who failed to respond to antibiotics for diverse conditions (H.Pylori wasnt among them in that particular study) did succeed when the antibiotic was combined with Bromelain. Here's reference to that survey of the literature:
Bromelain: A Literature Review and
Discussion of its Therapeutic Applications
by: Gregory S Kelly
(Alt Med Rev 1996;1(4):243-257)
=============================
So... I'm wondering if I really should be discontinuing Bromelain during the course of this triple therapy? It is a useful supplement for me.
Thank you
I usually take the supplement Bromelain to help with inflammation.
I've just read several medical articles which assert that Bromelain can potentiate Amoxicillin (and Tetracycline) and increase its levels in blood. In fact, it is often used to do just that.
My concern is that it might also increase its side-effects. Especially since I'm now taking 2 grams of it daily.
However , I also read-in journal article- that it can decrease side-effects of these antibiotics, as well as potentiating them:
===================
"Bromelain increases bioavailability and reduces the side effects that are associated with various antibiotics (12,13)"[
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4998156/
[cut and paste above link into browser for it to work]
==================
So far , this is only source I have found for reducing side effects. Much of the literature only references increasing blood levels of Amoxicillin.
An article surveying the medical literature on Bromelain does discuss its potentiating effects on some antibiotics and does discuss a study where some who failed to respond to antibiotics for diverse conditions (H.Pylori wasnt among them in that particular study) did succeed when the antibiotic was combined with Bromelain. Here's reference to that survey of the literature:
Bromelain: A Literature Review and
Discussion of its Therapeutic Applications
by: Gregory S Kelly
(Alt Med Rev 1996;1(4):243-257)
=============================
So... I'm wondering if I really should be discontinuing Bromelain during the course of this triple therapy? It is a useful supplement for me.
Thank you