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This is a non-profit website. We will try our best to help anyone that has question about H. pylori and their treatment. We shall provide the most accurate answer about H. pylori. You can help us by clicking here to keep this forum alive.
Some useful guides
How to post in the forum?
Management of Helicobacter pylori infection—the Maastricht V/Florence Consensus Report
The 5th Chinese Helicobacter treatment consensus
How long should I wait before doing follow up breath/stool test?
If you are confirmed with H. pylori, in your convenient time, please help us with the symptoms survey that you are experiencing.
Symptoms survey
(contributed by frostyfeet)
此网站免费然您阅读。若想分享心得或提问,请先注册。
若有困难注册,请联络站长 Marshall.centre(at)gmail(dot)com。标题请用 "Help needed for www.helico.com"
此网站不允许打广告。我们欢迎任何的讨论。但尽量不要推销没医学根据的网站,商品或治疗方案。
此网站是非盈利网站。我们会尽最大能力提供任何有关幽门螺杆菌的讯息。您的捐款可以让我们继续帮助更多的病人。
指南
如何贴文?
欧洲幽门螺杆菌治疗共识 5
第五次全国幽门螺杆菌感染处理共识报告
用药后,多久以后可以再做吹气测试?
Should you have any problem in posting, registering, or login, please do not hesitate to contact the admin at Marshall.centre(at)gmail(dot)com. In the subject, please use "Help needed for www.helico.com"
Advertisement is not allowed. While we encourage discussion, please try not to promote your website, goods, or unproven treatment here.
This is a non-profit website. We will try our best to help anyone that has question about H. pylori and their treatment. We shall provide the most accurate answer about H. pylori. You can help us by clicking here to keep this forum alive.
Some useful guides
How to post in the forum?
Management of Helicobacter pylori infection—the Maastricht V/Florence Consensus Report
The 5th Chinese Helicobacter treatment consensus
How long should I wait before doing follow up breath/stool test?
If you are confirmed with H. pylori, in your convenient time, please help us with the symptoms survey that you are experiencing.
Symptoms survey
(contributed by frostyfeet)
此网站免费然您阅读。若想分享心得或提问,请先注册。
若有困难注册,请联络站长 Marshall.centre(at)gmail(dot)com。标题请用 "Help needed for www.helico.com"
此网站不允许打广告。我们欢迎任何的讨论。但尽量不要推销没医学根据的网站,商品或治疗方案。
此网站是非盈利网站。我们会尽最大能力提供任何有关幽门螺杆菌的讯息。您的捐款可以让我们继续帮助更多的病人。
指南
如何贴文?
欧洲幽门螺杆菌治疗共识 5
第五次全国幽门螺杆菌感染处理共识报告
用药后,多久以后可以再做吹气测试?
Basic Science / Molecular Epidemiology / Evolution 基础研究 / 分子传播学 / 进化
Moderator: barjammar
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Toxins (esp. CagA and VacA)
CagA was the first protein antigen identified as a marker for the more evil type of H.pylori. cagA is one of about 30 genes in Cag pathogenicity island (cagPAI). These genes form a secretion system which injects CagA protein into cells where it causes disorganised cellular structure due to "growth factor like" effects.
VacA is a toxin which causes vacuolation of epithelial cells (bubbles within) when H.pylori attaches. VacA is a activated in acid to form a membrane pore which causes cells to become leaky, especially to urea. It also suppresses some of the immune response allowing H.pylori to persist.
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Other Evil Genes (babA, dupA, NAP etc)
Numerous other genes increase attachment, invasion, neutrophil attraction, survival and/or persistance of H.pylori in the gastric mucosa.
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Genomics of Helicobacters
One of the first bugs to be sequenced, H.pylori has a small genome (1.6 MD) befitting its lifestyle in a hostile acidic mucosal niche. Of the 1500 genes, 750-1000 are essential, the others are different in each strain. Hp has an "open pan-Genome" which means the more strains you look at the more genes you will find - i.e. you will never have a complete set of all its possible genes!
Moderator: barjammar - 3 Topics
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Re: On the contrary, many of …
by zefron View the latest post
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Animal Models of Hp
The initial animals infected with human Hp were germ free piglets. After that beagle puppies, pigs, mice, cats and, best of all, Mongolian Gerbils. The latter animals develop ulcers and stomach tumours in the presence of salt and carcinogens - similar to humans. There is much work to be done in this area.
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Re: My Dog Died Because of Un…
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Other Basic Sciences of Hp
Many more basic science categories can be added. If we have some good entries here we can expand the topic list.
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